Rare Form Of Eye Cancer Plagues Two States

by Crystal J

A rare form of eye cancer has struck a group of people in two locations in North Carolina and Alabama, confounding medical experts who are trying to determine whether the cases are linked.

Ocular melanoma typically affects 6 out of every 1 million people, but doctors have found dozens of cases where those affected have ties to either Huntersville, N.C., or Auburn, Ala. Many of those diagnosed attended Auburn University between 1983 and 2001 — at least three of them were friends.

At least 38 people who went to Auburn have reported being diagnosed with the disease, according to a Facebook page created by the patients. In Huntersville, at least 18 patients were identified in a formal investigation.

The Alabama Department of Health has declined to call the cases a cancer cluster yet, but researchers are investigating to determine whether there is a common cause for the diagnoses. A cluster is a higher-than-average number of cases identified in one particular geographic area over a limited period of time.

Unlike skin melanoma — which has been diagnosed more than 90,000 times this year — doctors typically see only 2,500 cases of ocular melanoma annually, says Dr. Marlana Orloff, an oncologist at the Sidney Kimmel Cancer Center at Thomas Jefferson University in Philadelphia, who is studying the cases. She says it is unlikely this group of patients got the cancer from sun or other UV light exposure.

“If it were something as simple as the sun or as simple as tanning bed use, we wouldn’t necessarily, I think, be seeing it in such restricted geographic locations,” Orloff tellsHere & Now‘s Robin Young.

Juleigh Green was the first person among at least 36 former Auburn students to be diagnosed with the disease in 1999. Two friends, Allison Allred and Ashley McCrary, were also treated for the cancer, and Green and Allred had to undergo eye removal surgery. The women told NBC’s Today show they were diagnosed just a few years after graduating from college.

“When I was diagnosed, I kept wanting to talk to someone who had been through this before and had done well,” Green told CNN. “But it seemed like nobody had heard of this or had any connection with anyone who had this, and that’s when I realized how incredibly rare it was.”

According to the Ocular Melanoma Foundation, the cancer develops from cells that produce the dark-colored pigment melanin. These cells are found in the skin, hair, eyes and lining of some internal organs.

The symptoms of ocular melanoma include dark spots on the eyes, flashes or blurry vision, Orloff says. Sometimes people have no symptoms at all, and the condition is identified during a routine eye exam.

The primary treatment — radiation therapy — is very effective, Orloff says. But in about half of patients, the cancer recurs, metastasizing or spreading to other parts of the body, most commonly in the liver.

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